Nanoscale
Tunable naphthalimide-based fluorogenic intracellular nanoaggregates trigger ROS-mediated DNA damage and apoptosis in triple-negative breast cancer cells.
Arpita Hota, Aakash Ravikant Likhar, Sadiya Tanga, Arkadeep Karmakar, Deepak Asthana, Basudeb Maji
Published: 202610.1039/d5nr04029a
Abstract
We report new classes of naphthalimide homodimers with diverse linker chemistry that help fine-tune molecular aggregation properties in aqueous medium and cells. Naphthalimide derivatives with positively charged linkers show nanoaggregation and excim…
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