Nanoscale
Dual modulation of lysosomal integrity via alkalization and lipid peroxidation: a promising strategy for tumor inhibition.
Donglin Liu, Jianzhi Mao, Yuying Dai, Kailin Li, Qiwei Tian, Fengfeng Xue, Shiping Yang, Lu An
Published: 202610.1039/d5nr03792a
Abstract
Lysosomes, characterized by their high abundance, large size, and fragile membranes in cancer cells, have attracted increased attention as promising targets for therapeutic strategies involving lysosomal membrane permeabilization (LMP). However, the…
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