Nanoscale
In situ programming of CAR-macrophages via a polyplex nanomaterial and STING activation for triple-negative breast cancer immunotherapy.
Armaan Siddiqui, Hemavathi Dhandapani, Aijaz Rather, Arvind Ingle, Deepak Sharma, Prakriti Tayalia
Published: 202610.1039/d5nr03762j
Abstract
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer characterized by the absence of an estrogen receptor, a progesterone receptor, and HER2. Current treatment modalities, including surgery, chemotherapy, and radiotherapy, are…
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