NanoscaleAnimalsAdministrationIntranasalRespiratory Syncytial Virus VaccinesRNA
An optimized intranasal LNP formulation for potent immune responses of mRNA-based RSV vaccines.
Yan Li, Haiyan Long, Chunxia Wang, Jiayi Weng, Ziyun Kuang, Yucai Peng
Published: 202510.1039/d5nr01452b
Abstract
Nasal immunoglobulin A (IgA) has been shown to be associated with the prevention of respiratory syncytial virus (RSV) infection and viral replication. However, generating strong mucosal IgA for mRNA vaccines administered via intramuscular injection h…
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