Lab on a chip
CombiCTx: screening diffusion gradients of anti-cancer drug combinations.
Christina Stelzl, Ada Lerma-Clavero, Selina Camenisch, Benoit Simon, Olle Eriksson, Oliver Degerstedt, Hans Lennernäs, Femke Heindryckx, Johan Kreuger, Paul O'Callaghan
Published: 202610.1039/d5lc00686d
Abstract
The reduced effectiveness of chemotherapy in many patients undergoing treatment highlights the need for novel drug combinations that target drug resistance mechanisms contributing to tumor survival. Dynamic conditions within the tumor microenvironmen…
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