Lab on a chipHumansColorectal NeoplasmsAntineoplastic AgentsLab-On-A-Chip DevicesCell Line
Repeated exposure of anticancer agents to tumorspheres in open-surface microwell arrays for modeling chemotherapy-induced dormancy in colorectal cancer.
Hui Kang, Xiaogang Wang, Weijie Ye, Yanzhang Luo, Jueming Chen, Ziqing Ma, Jiayu Li, Lihui Wang, Dongguo Lin, Dayu Liu
Published: 202610.1039/d5lc00453e
Abstract
Dormant cancer cells (DCCs) serve as crucial contributors to tumor drug resistance and recurrence; however, the mechanisms underlying their formation and biological characteristics remain inadequately understood. The establishment of reliable DCC mod…
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