Food & functionAnimalsChlorogenic AcidNF-E2-Related Factor 2FerroptosisRats
Chlorogenic acid alleviates chronic restraint stress-induced liver injury potentially via Nrf2-mediated inhibition of ferroptosis and mitochondrial apoptosis.
Haoyang Tan, Yaxin Ji, Xin Cheng, Jiahuan Hu, Xiaoqing Yu, Jiaxing Wang, Haotian Yang, Shuai Zhang, Guofeng Feng, Wenjing Jiao, Yuan Zhao, Honggang Fan
Published: 202610.1039/d5fo04627k
Abstract
Chronic stress primarily induces liver injury through excessive production of reactive oxygen species (ROS), yet the complete underlying mechanisms remain elusive. This study demonstrates that chlorogenic acid (CGA), a natural antioxidant, markedly a…
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