Food & functionAnimalsToll-Like Receptor 4AspartameMiceNF-kappa B
Transcriptomic evidence of hypothalamic neuroinflammation in mice due to aspartame exposure through the TLR4/NF-κB/NLRP3 pathway.
Wenyu Yang, Tong Tong, Qiqi Li, Wenhui Ye, Wei Wei
Published: 202610.1039/d5fo00831j
Abstract
The use of aspartame (ASP) instead of sugar is increasing. ASP exposure has been shown to affect the hypothalamus. However, whether it causes hypothalamic inflammation in mice and the specific molecular mechanisms are unknown. Here, we established an…
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