Dalton transactions (Cambridge, England : 2003)HumansAntineoplastic AgentsPyrrolesCisplatinCell Line
Platinum(II) complexes of fluorinated pyrrole carbothioamides: enhanced anticancer activity and overcoming cisplatin resistance.
Haiming Tang, Chen Chen, Yuhang Fu, Tong Sun, Li Yin, Mingyuan He, Qin Fu, Qin Li, Yu Liu, Ziyun Chen, Stephen M F Jamieson, Tilo Söhnel, Christian G Hartinger
Published: 202510.1039/d5dt02290h
Abstract
A series of fluorinated pyrrole-derived thioamide ligands was synthesized via a solvent-free reaction of (substituted) pyrrole with various aryl isothiocyanates. Subsequent reactions of these ligands with cis-[PtCl2(PPh3)2] afforded a set of charge-n…
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