Physical chemistry chemical physics : PCCPNeutron DiffractionHumansAntineoplastic AgentsCisplatinSerum Albumin
Probing drug pharmacokinetics using neutron scattering techniques.
Clara B Martins, Mona Sarter, Ana L M Batista de Carvalho, Victoria García-Sakai, Tilo Seydel, Jacques Ollivier, Luís A E Batista de Carvalho, Maria P M Marques
Published: 202610.1039/d5cp03679h
Abstract
Quasi-elastic neutron scattering was applied to the study of human serum albumin metalation by anticancer drugs, with a specific focus on understanding the effects on the protein dynamics at the atomic scale. Two drugs were studied, a dinuclear Pd-co…
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