Chemical communications (Cambridge, England)Photosensitizing AgentsHumansPhotochemotherapyCell NucleusNeoplasms
The next Frontier of photodynamic therapy: nuclear-targeted small-molecule photosensitizers for precise tumor cell elimination.
Yang Tian, Jianfen Wang, Fangjun Huo, Caixia Yin
Published: 202610.1039/d5cc05711f
Abstract
A photosensitizer (PS), which can generate reactive oxygen species (ROS) under laser irradiation, is a decisive factor in the efficacy of PDT. However, the ROS generated by PS has a short lifetime (<40 ns) and a small diffusion distance (<20 nm), whi…
Preview only. Read the full abstract at the source