Acetylacetone-modified ubiquitin C-terminus enables specific capture of sulfenylated deubiquitinases.

Activity-based ubiquitin (Ub) probes have recently emerged as effective tools for profiling deubiquitinases (DUBs) in their reduced, catalytically active state; however, most existing Ub probes fail to capture oxidatively modified DUBs-such as sulfen…

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