Chemical communications (Cambridge, England)PhotochemotherapyHumansRutheniumCoordination ComplexesAntineoplastic Agents
Red-light excitation of a Ru(II)-Pt(II) tetranuclear complex for combined photoactivated chemotherapy and photodynamic therapy.
Pia Siekierski, Eleni Michaltsis, Julia Schleisiek, Nicolás Montesdeoca, Johannes Karges
Published: 202510.1039/d5cc05177k
Abstract
We report the synthesis and biological evaluation of a tetranuclear Ru(II)-Pt(II) complex activated by red light (630 nm). Upon irradiation, the Ru(II) center photo-catalytically generates singlet oxygen while simultaneously releasing Pt(II) moieties…
Preview only. Read the full abstract at the source