Chemical communications (Cambridge, England)IridiumPhotochemotherapyHumansCoordination ComplexesLigands
Cyclometallated iridium(III) complexes: ligand-driven selectivity for chemotherapy and photodynamic therapy.
Eva Morales-Pioz, Marta Redrado, Andrea Benedi, Araceli de Aquino, Pilar García-Orduña, María Royo-Cañas, Javier Godino, I Marzo, Laura Rodríguez, M Concepción Gimeno, Vanesa Fernández-Moreira
Published: 202510.1039/d5cc04768d
Abstract
This study explores two cyclometallated Ir(III) complex families with distinct therapeutic profiles. Benzothiophene derivatives (1, 2) exhibit potent antiproliferative character in the dark, favoring chemotherapy, while benzothiazole analogs (3 and 4…
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