Chemical communications (Cambridge, England)HumansDNAEndonucleasesProteinsGene Editing
HUH endonuclease-mediated DNA-protein conjugates: sequence-specific tools and cellular applications.
Xiaowei Huang, Haokun Li, Jiajun Du, Wenxue Xie, Yuanyuan Liu, Yingwu Lin, Hang Xing
Published: 202510.1039/d5cc04628a
Abstract
This highlight review article summarizes recent advances in employing HUH endonucleases as self-labeling protein tags for the sequence-specific covalent conjugation of unmodified ssDNA and examines their applications in cellular studies via engineere…
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