Chemical communications (Cambridge, England)Fluorescent DyesHumansViscosityOptical ImagingAnimals
A viscosity-activated and tumor-specific NIR probe for precise imaging of cancer cells.
Xue Wu, Lingling Cao, Qiuyue Zhao, Junjie Kou, Ying Li, Fanpeng Kong, Bo Tang
Published: 202510.1039/d5cc04607f
Abstract
We developed DHX-Biotin-V, an NIR fluorescent probe that selectively detects viscosity with minimal interference from polarity or pH. It targets biotin receptors to enter tumor cells, where its fluorescence activates specifically in high-viscosity mi…
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