Chemical communications (Cambridge, England)
Palladium-catalyzed Heck/polyfluoroarylation of alkene-tethered carbamoyl chlorides with polyfluoroarenes.
Chen Chen, Zi-Yi Wang, Xin-Yu Hu, Xiao-Xu Zhang, Yan-Ping Zhu, Chunjie Ni, Bolin Zhu
Published: 202510.1039/d5cc04604a
Abstract
We developed a Pd-catalyzed Heck/polyfluoroarylation cascade to synthesize polyfluoroarylated oxindoles with all-carbon quaternary centers from alkene-tethered carbamoyl chlorides. The reaction was extended to a three-component one-pot protocol using…
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