Chemical communications (Cambridge, England)HydroxylationHumansBoronBiocompatible MaterialsCell Survival
Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility.
Satoshi Yamamoto, Rikuto Nakajima, Yuya Hirai, Yumiko K Kawamura, Yoshimasa Makita, Taro Kitazawa, Mutsumi Kimura, Yu Kitazawa
Published: 202610.1039/d5cc04085j
Abstract
[B12I12]2- exhibits potent membrane transport yet high cytotoxicity. Stepwise hydroxylation moderates chaotropicity, balancing permeability and biocompatibility. Notably, mono-hydroxylation retains transport activity while minimizing toxicity, wherea…
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