Analytical methods : advancing methods and applicationsAnimalsLysosomesFluorescent DyesHydrogen-Ion ConcentrationOxidative Stress
A water-soluble and lysosome-targeted pH fluorescent probe for analytical monitoring of cellular oxidative stress and in vivo non-invasive imaging of alcoholic gastritis in mice.
Yukun Zhang, Lie Li, Ruiyuan Liu, Jinqing Qu
Published: 202510.1039/d5ay01472g
Abstract
As a key acidic organelle, the pH homeostasis of lysosomes is critical for cellular functions. Existing pH fluorescent probes generally face limitations such as poor water solubility, insufficient targeting, and narrow pH response range, which hinder…
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