EMBO molecular medicine
Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities.
Lennart Roos, Aida Garrido-Charles, Niels Albrecht, Anna Vavakou, Alexey Alekseev, Martina Bleyer, Anupriya Thirumalai, Artur Mittring, Theocharis Alvanos, Antoine T Huet, Ernst Bamberg, Kathrin Kusch, Bettina J Wolf, Tobias Moser, Thomas Mager
Published: 202510.1038/s44321-025-00350-z
Abstract
Optogenetics allows versatile control of excitable cell networks, which advances basic science research and drives the development of future medical applications. Fast-closing channelrhodopsins (ChRs) are required for high temporal fidelity of neuros…
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