Molecular systems biology
Predicting the protein interaction landscape of a free-living bacterium with pooled-AlphaFold3.
Horia Todor, Lili M Kim, Jürgen Jänes, Hannah N Burkhart, Seth A Darst, Pedro Beltrao, Carol A Gross
Published: 202610.1038/s44320-026-00189-7
Abstract
Accurate prediction of protein complex structures by AlphaFold3 and similar programs has been used to predict the presence of protein-protein interactions (PPIs), but this technique has never been applied to an entire genome due to onerous computatio…
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