Communications medicine
IdentifiHR predicts homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expression.
Ashley L Weir, Samuel C Lee, Mengbo Li, Ahwan Pandey, Chin Wee Tan, Dale W Garsed, Susan J Ramus, Nadia M Davidson
Published: 202610.1038/s43856-026-01387-y
Abstract
BACKGROUND: Approximately half of all high-grade serous ovarian carcinomas (HGSCs) have a therapeutically targetable defect in homologous recombination (HR) DNA repair. While there are genomic and transcriptomic methods, developed for other cancers,…
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