Communications medicine
Transcriptomic profiling and machine learning uncover gene signatures of psoriasis endotypes and disease severity.
Ashley Rider, Henry J Grantham, Graham R Smith, David S Watson, John Casement, Simon J Cockell, Jack Gisby, Amy C Foulkes, Rafael Henkin, Wasim A Iqbal, Tom Ewen, Shoba Amarnath, Sandra Ng, Paolo Zuliani, Nick Dand
Published: 202610.1038/s43856-025-01325-4
Abstract
BACKGROUND: Despite increased understanding of psoriasis pathogenesis, molecular classification of clinical phenotypes and disease severity is poorly defined. Knowledge gaps include whether molecular endotypes of psoriasis underlie distinct clinical…
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