Nature computational science
Predicting drug responses of unseen cell types through transfer learning with foundation models.
Yixuan Wang, Xinyuan Liu, Yimin Fan, Binghui Xie, James Cheng, Kam Chung Wong, Peter Cheung, Irwin King, Yu Li
Published: 202510.1038/s43588-025-00887-6
Abstract
Drug repurposing through single-cell perturbation response prediction provides a cost-effective approach for drug development, but accurately predicting responses in unseen cell types that emerge during disease progression remains challenging. Existi…
Preview only. Read the full abstract at the source