Nature computational science
Generalized design of sequence-ensemble-function relationships for intrinsically disordered proteins.
Ryan K Krueger, Michael P Brenner, Krishna Shrinivas
Published: 202510.1038/s43588-025-00881-y
Abstract
The design of folded proteins has advanced substantially in recent years. However, many proteins and protein regions are intrinsically disordered and lack a stable fold, that is, the sequence of an intrinsically disordered protein (IDP) encodes a vas…
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