Nature agingCellular SenescenceT-Box Domain ProteinsAnimalsAgingCD4-Positive T-Lymphocytes
CD4 T cells acquire Eomesodermin to modulate cellular senescence and aging.
Yehezqel Elyahu, Ilana Feygin, Ekaterina Eremenko, Noa Pinkas, Alon Zemer, Amit Shicht, Omer Berner, Roni Avigdory-Meiri, Anna Nemirovsky, Keren Reshef, Lior Roitman, Valery Krizhanovsky, Alon Monsonego
Published: 202510.1038/s43587-025-00953-8
Abstract
Aging is characterized by the progressive deterioration of tissue structure and function, leading to increased vulnerability to diseases. Senescent cells (SCs) accumulate with age, but how the immune system regulates their burden is unclear. Here we…
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