Nature metabolismHumansInsulin ResistanceLipid MetabolismNon-alcoholic Fatty Liver DiseaseGenetic Predisposition to Disease
Human genetics of steatotic liver disease: insights into insulin resistance and lipid metabolism.
Rosellina M Mancina, Luca Valenti, Stefano Romeo
Published: 202510.1038/s42255-025-01394-8
Abstract
Metabolic-dysfunction-associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease or NAFLD) is a prevalent and heterogeneous condition affecting nearly 30% of the global population. MASLD is defined as excessive h…
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