Communications chemistry
Direct diazotization of indoles with 2-Methoxyethyl nitrite.
Airu Hashidoko, Taku Kitanosono, Yuki Nakao, Yasuhiro Yamashita, Shū Kobayashi
Published: 202610.1038/s42004-026-01910-1
Abstract
In pursuit of the reductive conversion of NO in organic synthesis, this study presents the direct diazotization of indoles using 2-methoxyethyl nitrite (MOE-ONO). Diazo compounds are invaluable intermediates in organic synthesis, serving as carbene p…
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