Communications biology
Glioblastoma stem cells show transcriptionally correlated spatial organization.
Shamini Ayyadhury, Patty Sachamitr, Michelle M Kushida, Nicole I Park, Fiona J Coutinho, Owen Whitley, Panagiotis Prinos, Cheryl H Arrowsmith, Peter B Dirks, Trevor J Pugh, Gary D Bader
Published: 202610.1038/s42003-026-09566-2
Abstract
Glioblastoma (GBM) is an aggressive brain cancer with a poor survival rate. Despite hundreds of clinical trials, there is no effective targeted therapy. Glioblastoma stem cells (GSCs) are an important GBM model system. In culture, these cells form sp…
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