Communications biology
Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking.
Lijun Zheng, Xinyi Duan, Wenyi Huang, Yuhao Luo, Yufei Wu, Qihui Lin, Xiaohua Wu, Lu Han, Wanhua Shen
Published: 202610.1038/s42003-025-09507-5
Abstract
Environmental light significantly influences neural development, yet the specific mechanisms underlying the effects of prolonged visual experience on homeostatic synaptic scaling remain unclear. Using manipulated ambient light conditions, we observed…
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