Communications biology
Multimodal epigenetic and enhancer network remodeling shape the transcriptional landscape of human beige adipocytes.
Sarah Hazell Pickering, Natalia M Galigniana, Mohamed Abdelhalim, Anita L Sørensen, Julia Madsen-Østerbye, Manuela Zucknick, Philippe Collas, Nolwenn Briand
Published: 202610.1038/s42003-025-09469-8
Abstract
Epigenetic regulation is a key determinant of adipocyte fate, driving the differentiation toward white or thermogenic beige phenotypes in response to environmental cues. To dissect the mechanisms orchestrating this plasticity in human adipocytes, we…
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