Communications biology
Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition.
Chuwei Lin, Catherine M Sniezek, Christopher D McGann, Rashmi Karki, Ross M Giglio, Benjamin A Garcia, José L McFaline-Figueroa, Devin K Schweppe
Published: 202610.1038/s42003-025-09455-0
Abstract
Epigenetic inhibitors exhibit powerful antiproliferative and anticancer activities. However, cellular responses to small-molecule epigenetic inhibition are heterogeneous and dependent on factors such as the genetic background and metabolic state of c…
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