Communications biology
Enhancing the breadth of protection in mice with a multivalent influenza vaccine.
Xiang Wang, Yixin Niu, Ying Hu, Caihong Zhu, Xi Yang, Hongyang Shi, Yao Yan, Ping Zhou, Longfei Ding, Miaomiao Zhang, Mangteng Wu, Shubing Tang, Man Xing, Dongming Zhou
Published: 202610.1038/s42003-025-09451-4
Abstract
The high mutation rate of the influenza virus poses a significant challenge to global health, highlighting the urgent need for broad-spectrum vaccines. Here, we engineered Ad-Hex, a pan-influenza vaccine comprising three chimpanzee adenoviral vectors…
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