Communications biology
Distinct membrane binding properties of the two non-visual arrestins.
Thomas D Killeen, Katelyn Tepper, Kyle W Miller, Yasmin Aydin, Ya Zhuo, Shuaitong Zhao, Jason M Conley, Rachel Tat, Candice S Klug, Adriano Marchese, Valerică Raicu, Qiuyan Chen
Published: 202610.1038/s42003-025-09428-3
Abstract
Membrane interactions play a crucial role in regulating arrestin activation and its binding to phosphorylated G protein-coupled receptors (GPCRs). Here, we combine in vitro biophysical approaches with cell-based fluorescence intensity fluctuation ana…
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