Scientific reports
Association of a five-metabolite and early-symptom profile with Parkinson's disease and its clinical progression.
Juan José Oropeza Valdez, José Pedro Elizalde-Díaz, Osbaldo Resendis Antonio, Jaquelin Leyva -Hernández, Laura Adalid-Peralta, Mayela Rodríguez-Violante, Rupasri Mandal, David S Wishart, Yamilé López-Hernández, Eduardo Martínez -Martínez
Published: 202610.1038/s41598-026-36756-z
Abstract
Parkinson's disease (PD) urgently requires blood-based markers that flag pathology before disabling motor decline. This study measured absolute concentrations of 144 plasma metabolites in 20 neurologically healthy adults and in 40 PD patients clinica…
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