Scientific reports
TET1 suppresses hepatocellular carcinoma progression by modulating the PI3K/Akt signaling pathways.
Shuaiyong Qi, Ming Chen, Zhixian Ding, Mike Dai, Lusheng Wang, Jie Chen, Yu Tang, Mengxue Hu, Yafei Li, Kemeng Tan, Lili Li, Hui Jiang, Heng Tang
Published: 202610.1038/s41598-026-36334-3
Abstract
Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with a poor prognosis, underscoring the urgent need to identify novel therapeutic targets. The epigenetic regulator TET1, a key enzyme involved in active DNA demethylation, has been imp…
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