Scientific reports
Expression of sphingosine-1-phosphate receptor 1 in the brain of fatal cerebral malaria.
Charit Srisook, Rungrat Nintasen, Chuchard Punsawad, Supattra Glaharn, Tachpon Techarang, Parnpen Viriyavejakul
Published: 202610.1038/s41598-026-36072-6
Abstract
The signaling pathway activated by sphingosine-1-phosphate (S1P) through S1P receptor 1 (S1PR1) plays specific roles in regulating vascular integrity and preventing vascular leakage during inflammatory response. Endothelial cell barrier dysfunction h…
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