Scientific reports
Proteomic analysis of endothelial progenitor cells secretome identifies Serpine 1 as a potent regulator of osteogenesis.
Thabet Asbi, Tal Tamari, Ofri Doppelt-Flikshtain, Oshrat Regev-Yehishalom, Itay Zusmanovich, Amin Younis, Tahel Ogen, Tal Berg, Havazelet Bianco-Peled, Hadar Zigdon-Giladi
Published: 202610.1038/s41598-026-36048-6
Abstract
Endothelial progenitor cells (EPCs) exert potent paracrine effect on bone regeneration, yet the specific protein mediators remain incompletely characterized. Through proteomic profiling of EPC-conditioned medium, we identified eight highly secreted p…
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