Scientific reports
Engrailed 1 promotes immune evasion and chemoresistance in glioma through single cell and CeRNA network analyses.
Zhen Jia, Yanchao Wang, Jieqin Yao, Liuyue Zhang, Xingbo Liang, Tao Wen, Wenle Li, Zhenzhe Li
Published: 202610.1038/s41598-026-35553-y
Abstract
Immune evasion is a major barrier to effective glioma treatment, yet the molecular drivers contributing to this process remain insufficiently understood. Engrailed-1 (EN1), a developmental transcription factor, has recently emerged as a potential onc…
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