Scientific reports
Indirubin treatment was associated with modulation of the PI3K/AKT and MAPK pathways and induction of apoptosis and autophagy.
Xiuchao Xie, Chang Liu, Xiaoling Liu, Lin Hou, Ya Zhang, Lin Huang, Weidong Peng, Yu Liu
Published: 202610.1038/s41598-026-35382-z
Abstract
This study investigated the effects of indirubin on autophagy and apoptosis in cervical cancer models, with a focus on elucidating the underlying molecular mechanisms. A xenograft tumor model in BALB/c-Nude mice and in vitro experiments using HeLa ce…
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