Synthesis and characterization of palladium nanoparticles modified UiO66 metalorganic framework for the synthesis of pyridine derivatives.

A novel metal-organic framework, Pd/EDTA/UiO-66, has been designed by chemically linking UiO-66-NH2 with ethylenediaminetetraacetic acid and palladium (EDTA/Pd) to enable the efficient synthesis of pyridine derivatives. This framework was fabricated through a solvothermal method, incorporating pre-synthesized Pd nanoparticles directly into its structure. Comprehensive characterization was carried out using a range of analytical techniques, including ICP, XRD, SEM, TGA, EDX, and BET. Remarkably, Pd/EDTA/UiO-66 exhibited superior catalytic performance, achieving excellent efficiency under mild reaction conditions. In addition, the catalyst demonstrated outstanding recyclability, maintaining high activity and yields over at least four consecutive cycles. Key benefits of this method include the use of a green reaction medium, simplified separation and workup processes, excellent reusability of the nanocatalyst, and reduced reaction times.