Scientific reports
Preparation of spleen aminopeptide-loaded pH-responsive oral hydrogel microspheres for improving recurrent respiratory infection in children.
Aqin Wang, Zhengbing Zhou, Zhou Hang, Zhengbing Lyu, Jingchun Yang, Lu Zhang, Meng Wang, Wei Liu, Liqiang Zou, Jun Yu
Published: 202610.1038/s41598-025-34890-8
Abstract
Direct oral intervention of spleen aminopeptide (SA) would be limited because of its varied swelling and release rate in different pH environments of digestive fluids. Herein, pH-responsive hydrogel microspheres (3.67 ± 0.04 mm) with positive SA-load…
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