Scientific reports
Oleic acid alleviates the pathogenesis of lupus by suppressing the activation of TLR signaling pathways through the STAT3/IL-10 axis.
Yuxin Hu, Yucai Xiao, Yangzhe Gao, Zhengyi Zhang, Tianqi Zhao, Shuo Zhao, Jiakun Liu, Huabao Xiong, Yonghong Yang, Guanjun Dong, Lu Yu
Published: 202610.1038/s41598-025-34755-0
Abstract
Toll-like receptors (TLRs) play a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE) by regulating the activation and differentiation of immune cells. Oleic acid (OA), the predominant monounsaturated fatty acid found in adipose ti…
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