Scientific reports
Caffeic acid phenethyl ester induced apoptosis in chronic myeloid leukemia cells by inhibiting mitochondrial complex I.
Meng Li, Dongxue Liu, Zhiwei Zhang, Biqian Fu, Ruihua Xiong, Han Han, Ying Zhang, Zhihua Peng, Yuhe Lei, Yanli Fu
Published: 202610.1038/s41598-025-34553-8
Abstract
Chronic myeloid leukemia (CML) is an oncogenic hematologic disorder defined by the BCR-ABL1 fusion gene, which initiates pathological proliferation of myeloid lineage cells. While tyrosine kinase inhibitors (TKIs) have substantially improved clinical…
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