Scientific reports
Elevated serotonin receptor 2A signaling restores learning and memory in a Fragile X syndrome model.
Yuchen Du, Vanessa K Miller, Andrew J Mellies, Kendal Broadie
Published: 202610.1038/s41598-025-34492-4
Abstract
Serotonin (5-hydroxytryptamine, 5-HT) has central roles enabling learning and memory, particularly via serotonin receptor 2A (5-HT2AR) signaling. Drosophila Fragile X syndrome model (dfmr1 null mutant) studies reveal impaired learning and memory, whi…
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