Scientific reportsHumansLeprosyTranscriptomeBiomarkersMale
Advancing leprosy risk prediction through identification of a whole blood host transcriptomic biomarker signature including non-coding genes.
Matheus Rogerio Almeida, Elisa Gherardi, Suzanne van Veen, Luca Maharavo, Aart Rosmolen, Emma van Eerde, Fons J Verbeek, Marufa Khatun, Santosh Soren, Abu Sufian Chowdhury, Khorshed Alam, Johan Chandra Roy, Cristiana Santos de Macedo, Anouk van Hooij, Annemieke Geluk
Published: 202510.1038/s41598-025-33878-8
Abstract
Leprosy is a debilitating disease that requires early detection for effective control, yet diagnosis still relies on clinical signs. Previous RNA-Seq analysis of coding genes from leprosy patients' household contacts (HHC) who developed leprosy (prog…
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