Nature structural & molecular biologyExonsRNA SplicingSpliceosomesHumansRNA Precursors
Gene regulation through exon junction complex modularity.
Elizabeth T Abshire, Lynne E Maquat
Published: 202510.1038/s41594-025-01724-0
Abstract
The exon junction complex (EJC) begins to assemble on the spliceosome, which deposits EJCs upstream of most exon-exon junctions during pre-messenger RNA (mRNA) splicing. EJCs acquire additional alternative modules that define heterogeneous EJCs durin…
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