Nature neuroscience
Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion.
Bharti Kukreja, Shin Jeon, Wuxinhao Cao, Bianca Rusu, Camille F Harrison, Shahrzad Ghazisaeidi, Nareh Tahmasian, Min Yi Feng, Rita Chan, Allison Loan, William B Johnston, Shreya Padhy, Seth Rakoff-Nahoum, Jing Wang, Yeong Shin Yim
Published: 202610.1038/s41593-025-02162-3
Abstract
Immune molecules and their cognate receptors are developmentally regulated in brain and dynamically expressed in the context of neurodevelopmental disorders. Despite the importance of immune molecules to brain wiring, a comprehensive map of the neuro…
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