Nature neuroscience
Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer's disease via dysregulation of CCK neurons.
Yang Zhou, Wen-Lian Li, Zhi-Qiang Liu, Wen-Qing Ai, Jia-Xin Kou, Hong-Wei Fan, Zhi-Tao Han, Ya-Zhuo Hu, Hong-Hong Zhang, Jian-Jun Jia, Yan Zeng, Zi-Yuan Guo, Heng-Ye Man, You-Ming Lu, Dan Liu
Published: 202510.1038/s41593-025-02137-4
Abstract
Somatosensory processing has been shown to be correlated with brain development and cognitive function, but whether and how tactile sensory deficits affect cognition decline remains unclear. Here we show that tactile function is impaired in individua…
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