Nature neuroscience
BOLD signal changes can oppose oxygen metabolism across the human cortex.
Samira M Epp, Gabriel Castrillón, Beijia Yuan, Jessica Andrews-Hanna, Christine Preibisch, Valentin Riedl
Published: 202510.1038/s41593-025-02132-9
Abstract
Functional magnetic resonance imaging measures brain activity indirectly by monitoring changes in blood oxygenation levels, known as the blood-oxygenation-level-dependent (BOLD) signal, rather than directly measuring neuronal activity. This approach…
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